학술논문
Nuclear receptors: how do they position in non-alcoholic fatty liver disease treatment?
Document Type
Editorial
Source
Subject
*NUCLEAR receptors (Biochemistry)
*FATTY liver
*THERAPEUTICS
*PHARMACOLOGY
*BILE acids
*GLUCOSE metabolism
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Language
ISSN
1478-3223
Abstract
The article focuses on the role of nuclear receptors (NR) in treatment of non-alcoholic fatty liver disease (NAFLD). It states that NR pharmacological manipulation showed improving results in animal models. It mentions that farsenoid X receptor (FXR) which is also known as NR1H4 is a sensor of bile acids. It highlights that FXR helps in glucose metabolism.