학술논문
A peroxiredoxin from Mycoplasma hyopneumoniae with a possible role in H2 O2 detoxification.
Document Type
Article
Source
Subject
*METABOLIC detoxification
*PEPTIDE antibiotics
*DETOXIFICATION (Alternative medicine)
*HYDROGEN peroxide
*DISINFECTION & disinfectants
*ESCHERICHIA coli
*THERAPEUTICS
*
*
*
*
*
*
Language
ISSN
1350-0872
Abstract
The article presents a study which evaluates the role of peroxiredoxin (MhPrx) in hydrogen peroxide detoxification. The study exposes the bacterium to reactive oxygen species (ROS) from its own metabolism to neutralize the pathogen. Finding shows that MhPrx is tightly related to the atypical 2-Cys peroxiredioxin taxon, and its coding DNA sequence was copied in Escherichia coli. Conclusion shows that recombinant MhPrx protects DNA from ROS-treated damage and plays a crucial role in infection.