학술논문

Precision Medicine in Bladder Cancer: Present Challenges and Future Directions.
Document Type
Article
Source
Journal of Personalized Medicine. May2023, Vol. 13 Issue 5, p756. 31p.
Subject
*INDIVIDUALIZED medicine
*BLADDER cancer
*NOSOLOGY
*MOLECULAR pathology
*CLINICAL medicine
*NANOMEDICINE
*DEEP brain stimulation
Language
ISSN
2075-4426
Abstract
Bladder cancer (BC) is characterized by significant histopathologic and molecular heterogeneity. The discovery of molecular pathways and knowledge of cellular mechanisms have grown exponentially and may allow for better disease classification, prognostication, and development of novel and more efficacious noninvasive detection and surveillance strategies, as well as selection of therapeutic targets, which can be used in BC, particularly in a neoadjuvant or adjuvant setting. This article outlines recent advances in the molecular pathology of BC with a better understanding and deeper focus on the development and deployment of promising biomarkers and therapeutic avenues that may soon make a transition into the domain of precision medicine and clinical management for patients with BC. [ABSTRACT FROM AUTHOR]