학술논문
Probing RNA structures and functions by solvent accessibility: an overview from experimental and computational perspectives.
Document Type
Article
Source
Subject
*RNA
*TERTIARY structure
*SOLVENTS
*RNA-protein interactions
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Language
ISSN
1467-5463
Abstract
Characterizing RNA structures and functions have mostly been focused on 2D, secondary and 3D, tertiary structures. Recent advances in experimental and computational techniques for probing or predicting RNA solvent accessibility make this 1D representation of tertiary structures an increasingly attractive feature to explore. Here, we provide a survey of these recent developments, which indicate the emergence of solvent accessibility as a simple 1D property, adding to secondary and tertiary structures for investigating complex structure–function relations of RNAs. [ABSTRACT FROM AUTHOR]