학술논문
Technological Development and Advances for Constructing and Analyzing Plant Pangenomes.
Document Type
Article
Source
Subject
*PAN-genome
*GENETIC variation
*SPECIES diversity
*DNA structure
*DNA sequencing
*NUCLEOTIDE sequencing
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Language
ISSN
1759-6653
Abstract
A pangenome captures the genomic diversity for a species, derived from a collection of genetic sequences of diverse populations. Advances in sequencing technologies have given rise to three primary methods for pangenome construction and analysis: de novo assembly and comparison, reference genome-based iterative assembly, and graph-based pangenome construction. Each method presents advantages and challenges in processing varying amounts and structures of DNA sequencing data. With the emergence of high-quality genome assemblies and advanced bioinformatic tools, the graph-based pangenome is emerging as an advanced reference for exploring the biological and functional implications of genetic variations. [ABSTRACT FROM AUTHOR]