학술논문

Hypocalcaemia in pharyngolaryngectomy: Preservation or autotransplantation of parathyroid glands.
Document Type
Article
Source
Laryngoscope Investigative Otolaryngology. Oct2021, Vol. 6 Issue 5, p1208-1213. 6p.
Subject
*AUTOTRANSPLANTATION
*ONCOLOGIC surgery
*PARATHYROID glands
*SURGICAL excision
*NECK dissection
*GLANDS
Language
ISSN
2378-8038
Abstract
Objective: To describe transient and permanent hypocalcaemia following partial and total pharyngolaryngectomy with parathyroid gland preservation or autotransplantation. Methods: Thirty patients underwent partial or total pharyngolaryngectomy by a single surgeon during the period 2009‐2020. Intraoperative parathyroid gland preservation or autotransplantation (where the gland appeared devascularized) was routinely performed. Calcium levels performed on day 1, 3 months, and at 12 months postoperatively were collected. Rates of transient and permanent hypocalcaemia were calculated. Results: A total of 13% of patients had transient hypocalcaemia, and 10% permanent hypocalcaemia. Rates of transient and permanent hypocalcaemia in total pharyngolaryngectomy were 14% and 14%, respectively. Partial pharyngectomy hypocalcaemia rates were 13% for transient and 0% for permanent. The majority of patients underwent salvage surgery for oncological resection, often following radiotherapy (63%). Ipsilateral hemithyroidectomy was preferred to total (57% vs 7%), with high rates of concurrent neck dissection (67%) and reconstruction (87%). Conclusion: This data supports preservation or autotransplantation of parathyroid glands as a means of reducing permanent postoperative hypocalcaemia. Level of Evidence: Level IV, case series, retrospective. [ABSTRACT FROM AUTHOR]