부산대학교 도서관

Peripheral neurological involvement can occur in 5% of B-cell lymphoma cases, mostly involving axonal sensorimotor neuropathies related to chemotherapy, infiltrative multifocal neuropathies, or paraproteinemia-associated complications, such as cryoglobulinemia or anti-MAG polyneuropathy [[1], [3]]. Importantly, in 2/3 patients with preexisting CIDP, IVIg (patient #2) and plasma exchange (patient #4) could be withdrawn. The diagnosis of lymphoma was established on bone marrow biopsy (BMB) in 6 patients and bone marrow aspirate (BMA) with immunophenotyping in 2 patients, revealing diffuse large B-cell lymphoma in 2 patients (#5 and 7) and low-grade B cell proliferation in 6 (lymphoplasmacytic lymphomas (patients #1, 2, 4) marginal zone lymphomas (patients #6 and 8) and small lymphocytic lymphoma (#3)). Three patients with preexisting CIDP (considered idiopathic thus far: #2, 3, and 4) underwent examinations because of a loss of benefit from usual therapy (all 3) along with the emergence of cranial nerve involvement (patient #4), altered general state (#2) or immune thrombocytopenia (#3). [Extracted from the article]