학술논문

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
Document Type
Article
Source
eLife. Jul2015, p1-25. 25p.
Subject
*TRANSCRIPTION factors
*PANCREATIC cancer
Language
ISSN
2050-084X
Abstract
The article presents the study that explores on the vital role of acinar-specific pancreas-specific transcription factor 1 (PTF1A) in the development of the ductal pancreatic adenocarcinoma and in safeguarding the pancreatic acinar population from environmental insults and oncogene activity.