부산대학교 도서관

Q fever is an important zoonotic disease worldwide. The main sources of human infection are inhalation of aerosols containing Coxiella burnetii bacteria and exposition to infected materials during parturition or slaughtering. The high-risk group includes people who work directly with infected livestock, such as farmers, veterinarians, veterinary medicine students, slaughterhouse and laboratory staff. Here we present a pilot study of risk-group human seroprevalence to C. burnetii in Latvia. The study included 240 sera samples — 190 from the risk groups and 50 from the control group. Samples were tested with Coxiella burnetii (Q-fever) Phase 1 and 2 IgG ELISA kits. All sera from the control group were negative. The seroprevalence among risk group persons was 8.04–11.54%. No statistically significant differences were observed between genders. The highest percentage of seropositive and equivocal sera samples (25%) were detected in age categories 39–48 years and 49–58 years. Working as a practicing veterinarian or former veterinarian was the only risk factor identified as statistically significant, and belonging to the risk group in general. The geographical distribution of seropositive risk group participants indicated that they tend to located more in the northern, central, and eastern part of the country. [ABSTRACT FROM AUTHOR]