학술논문
Preclinical stress research: where are we headed? An early career investigator’s perspective.
Document Type
Article
Author
Source
Subject
*PSYCHOLOGICAL stress
*PATHOLOGICAL psychology
*ANXIETY
*MENTAL depression
*POST-traumatic stress disorder
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Language
ISSN
1025-3890
Abstract
Stress is a major risk factor in the development of various psychiatric disorders such as depression, anxiety and post-traumatic stress disorder. The use of stress paradigms in preclinical contexts is essential to advance our understanding of the pathophysiology of these disorders. However, they are not without their limitations and in this commentary, we have examined some of the practical issues associated with their use. We also highlight some of the latest techniques to identify their neuromolecular correlates as well as the potentially important and integrative role of computational neuroscience. Finally, we share our perspective on future directions in the field of preclinical stress research. [ABSTRACT FROM AUTHOR]