학술논문

WNTs tune up the neuromuscular junction.
Document Type
Journal Article
Source
Nature Reviews Neuroscience. Sep2009, Vol. 10 Issue 9, p627-634. 8p. 4 Diagrams.
Subject
*MYONEURAL junction
*CELL determination
*NEMATODES
*NEUROTRANSMITTER receptors
*SYNAPSES
*NERVOUS system
Language
ISSN
1471-003X
Abstract
Although WNTs have been long thought of as regulators of cell fate, recent studies highlight their involvement in crucial aspects of synaptic development in the nervous system. Particularly compelling are recent studies of the neuromuscular junction in nematodes, insects, fish and mammals. These studies place WNTs as major determinants of synapse differentiation and neurotransmitter receptor clustering. [ABSTRACT FROM AUTHOR]