학술논문
Adjuvant Bisphosphonates and Breast Cancer Survival.
Document Type
Article
Author
Source
Subject
*BREAST cancer treatment
*DIPHOSPHONATES
*ADJUVANT treatment of cancer
*SURVIVAL analysis (Biometry)
*BONE diseases
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Language
ISSN
0066-4219
Abstract
Randomized trials have studied bisphosphonates in the adjuvant setting of early breast cancer to investigate their ability to prevent treatment-induced bone loss. Trial results have also suggested their potential to prevent disease recurrence and metastases. These trials are summarized in this review. A recent patient-level meta-analysis by the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) finds convincing evidence that adjuvant antiresorptive treatments provide persistent benefits to breast cancer patients in low-estrogen situations and should be considered an important part of the treatment algorithm. [ABSTRACT FROM AUTHOR]