학술논문

Graft-versus-host and graft-versus-leukemia reactions: a summary of the Seventh International Symposium held in Garmisch-Partenkirchen, Germany, February 22nd–25th, 2006, Tolerance and Immunity, an update on lymphoid malignancies.
Document Type
Article
Source
Bone Marrow Transplantation. Nov2006, Vol. 38 Issue 9, p593-607. 15p. 2 Diagrams.
Subject
*CONFERENCES & conventions
*BONE marrow transplant complications
*GRAFT versus host reaction
*STEM cell transplantation
*HOMOGRAFTS
*LYMPHOID tissue
*CHRONIC lymphocytic leukemia
*CANCER
LEUKEMIA immunology
Language
ISSN
0268-3369
Abstract
The Seventh International Symposium on graft-versus-host and graft-versus-leukemia reactions was held in Garmisch Partenkirchen (Germany, near Lake Riessersee) between January 22nd and 25th, 2006. A total of more than 100 invited participants (scientists and clinicians working in the area of allogeneic stem cell transplantation) discussed research in the area of lymphoid malignancies. Major topics of the 2006 meeting were lymphocyte biology, experimental systems, lymphoma pathogenesis, cellular therapy in vivo and vitro, idiotype-specific responses and graft-versus-malignancy reactions for lymphomas and multiple myeloma. Further highlights were immune responses to blasts of ALL, haploidentical transplantation, role of natural killer cells, clinical guidelines for allogeneic transplantation and adoptive immunotherapy in chronic lymphocytic leukemia and multiple myeloma, new antibody-mediated strategies. As can be seen in the summaries of the individual presentations, progress was made in the understanding of lymphoma biology and in the clinical application of graft-versus-lymphoma or graft-versus-myeloma effects. Each day was followed by round-table discussions, which summarized new data and challenged established concepts. The discussions resulted in new insights and projects for basic research and clinical transplantation.Bone Marrow Transplantation (2006) 38, 593–607. doi:10.1038/sj.bmt.1705499; published online 18 September 2006 [ABSTRACT FROM AUTHOR]