학술논문

Connection between Genetic and Clinical Data in Bipolar Disorder.
Document Type
Article
Source
PLoS ONE. Sep2012, Vol. 7 Issue 9, Special section p1-9. 9p.
Subject
*BIPOLAR disorder
*COMBINATORICS
*PERMUTATIONS
*GENETIC polymorphism research
Language
ISSN
1932-6203
Abstract
Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significantly associated with bipolar disorder. It has now been found that these clusters may be connected to clinical data. [ABSTRACT FROM AUTHOR]