학술논문
Human Peritoneal Macrophages From Ascitic Fluid Can be Infected by a Broad Range of HIV-1 Isolates.
Document Type
Article
Author
Source
Subject
*HIV infections
*MACROPHAGES
*CIRRHOSIS of the liver
*GENE expression
*GENETIC markers
*PHAGOCYTOSIS
*
*
*
*
*
Language
ISSN
1525-4135
Abstract
The article presents the study which examines the HIV-1 infection in human peritoneal macrophages from ascitic fluid. It states that macrophages are cells that are major target by HIV because they support both productive and latent HIV-1 infection. The study demonstrated that peritoneal macrophages (PMs) are rich in ascitic fluid of patients with liver cirrhosis. It indicates that PMs are expressed CD68, a differentiation marker, which displayed phagocytic activity.