부산대학교 도서관

Introduction: Pregnancy is a process that can cause several physiologic changes to the cardiovascular system such as ventricular hypertrophy and dilation of cardiac chambers. Although there are studies about pregnancy‐related changes in echocardiographic examination; there is no data about the long‐term effects of parity on these alterations. Therefore, we evaluated the long‐term effect of pregnancy on right ventricular (RV) dilation and RV hypertrophy and their relation to the parity number. Methods: This prospective study included a total of 600 women (200 consecutive women who had no parity, 200 women who had a parity number of 1 to 4 and 200 women who had a parity number of more than 4). Right chambers' measurements were compared between the groups. Results: In echocardiographic analysis, RV and right atrial dimensions and areas and RV wall thickness were higher in parous women. On the other hand, RV systolic function parameters were significantly lower in parous women. These significant changes showed a gradual increase or decrease by increasing parity number. By multivariate hierarchical logistic regression analysis, the four independent factors that increased the risk of RV dilation were age (OR: 1.16 CI: 1.10–1.20), body mass index (OR: 1.05, CI: 1.02–1.08), smoking (OR: 1.87, CI: 1.28–4.02), and giving a birth (OR: 3.94 CI: 1.82–8.81). There was also independent relationship between the number of parity and RV hypertrophy even after adjustment for several confounders. Conclusion: Pregnancy‐related physiological changes mostly resolve after delivery. This study about long‐term effects of pregnancy on RV has demonstrated that there is a significant relation between the number of parity and either RV dilation or RV hypertrophy. Each parity had also additive effect on these changes. [ABSTRACT FROM AUTHOR]