학술논문

Recombinant ADAMTS13 in Severe Neonatal Thrombotic Thrombocytopenic Purpura.
Document Type
Article
Source
New England Journal of Medicine. 12/22/2022, Vol. 387 Issue 25, p2391-2392. 2p.
Subject
*THROMBOTIC thrombocytopenic purpura
Language
ISSN
0028-4793
Abstract
The article discusses research which focused on two neonates with hereditary thrombotic thrombocytopenic purpura (TTP). Topics explored include the pathogenic ADAMTS13 genetic variants observed in the posthumous genetic analysis of one infant, the treatment options for hereditary TTP such as plasma infusions to replace ADAMTS13, and brief details about clinical trials of recombinant ADAMTS13.