학술논문
Ertapenem plus meropenem combination treatment in carbapenem-resistant Klebsiella pneumoniae bacteremia: an analysis of 53 cases.
Document Type
Article
Author
Önal, Uğur; Akyol, Deniz; Kaya, Arda; Başkol, Dilşah; Kenanoglu, Buse; Şanlıdağ, Gamze; Önal, Ayşe Uyan; Avşar, Cansu Bulut; Mert, Merve; Memetali, Seichan; Erdem, Hüseyin Aytaç; Bozkurt, Devrim; Şimşir, Adnan; Bozbıyık, Osman; Kahraman, Ümit; Özgiray, Erkin; Korkmaz, Pervin; Çilli, Feriha; Pullukçu, Hüsnü; Yamazhan, Tansu
Source
Subject
*CARBAPENEM-resistant bacteria
*ERTAPENEM
*KLEBSIELLA pneumoniae
*BACTEREMIA
*KLEBSIELLA infections
*URINARY tract infections
*MEROPENEM
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Language
ISSN
0934-9723
Abstract
Herein, we aimed to describe the outcomes of patients with blood stream infections due to carbapenem-resistant Klebsiella pneumoniae (CR-Kp) who received ertapenem plus meropenem combination treatment (EMCT). A total of 53 patients with culture proven CR-Kp bacteremia treated with ertapenem + meropenem were included. The patients with secondary bacteremia due to urinary tract infection exhibited a significantly lower 1-month mortality (OMM), particularly in those with microbiological eradication and those with end-of-treatment success. Salvage EMCT resulted in 49% 1-month survival. [ABSTRACT FROM AUTHOR]