학술논문
Generation of Novel Severe Acute Respiratory Syndrome Coronavirus 2 Variants on the B.1.1.7 Lineage in 3 Patients With Advanced Human Immunodeficiency Virus-1 Disease.
Document Type
Article
Author
Source
Subject
*HIV infections
*HIV-positive persons
*IN vitro studies
*SARS-CoV-2
*COVID-19
*GENETIC mutation
*IN vivo studies
*IMMUNOCOMPROMISED patients
*RISK assessment
*CASE studies
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Language
ISSN
1058-4838
Abstract
The emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is of public health concern in case of vaccine escape. Described are 3 patients with advanced human immunodeficiency virus (HIV)-1 and chronic SARS-CoV-2 infection in whom there is evidence of selection and persistence of novel mutations that are associated with increased transmissibility and immune escape. [ABSTRACT FROM AUTHOR]