학술논문
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placental Infection Is Associated With Massive Perivillous Fibrin Deposition at the Maternal-Fetal Interface: A Preliminary Study.
Document Type
Article
Author
Source
Subject
*REVERSE transcriptase polymerase chain reaction
*COVID-19
*PLACENTA diseases
*IMMUNOHISTOCHEMISTRY
*SEVERITY of illness index
*FIBRIN
*DISEASE risk factors
*PREGNANCY
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Language
ISSN
1058-4838
Abstract
We observed an increased frequency of massive perivillous fibrin deposition (MPFD) during the second coronavirus disease 2019 (COVID-19) pandemic wave dominated by the Alpha variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MPFD associated with 100% reverse transcription polymerase chain reaction (RT-PCR) positivity for SARS-CoV-2 and detection by immunohistochemistry. The Alpha variant was identified in all placentas with MPFD that could be sequenced. [ABSTRACT FROM AUTHOR]