학술논문

Into the unknown: Diagnosing mysterious brain lesions.
Document Type
Article
Source
Transplant Infectious Disease. Aug2022, Vol. 24 Issue 4, p1-13. 13p.
Subject
*BRAIN abscess
*BRAIN damage
*BARTONELLA henselae
*DIAGNOSIS
*GRAM-negative bacteria
CENTRAL nervous system infections
Language
ISSN
1398-2273
Abstract
In this inaugural clinicopathological conference, the invited experts discussed the diagnostic approach to central nervous system infections in immunocompromised hosts. The case presented involved a pancreas‐kidney transplant recipient with multiple brain abscesses caused by Bartonella henselae. CSF metagenomic next‐generation sequencing played a significant role in the diagnosis. Bartonella henselae is a gram‐negative zoonotic pathogen that causes cat‐scratch disease, which can be transmitted to humans through cat bites or scratches. Symptoms can vary in severity, correlating with the patient's immune status. Visceral organ involvement, ocular involvement, and neurological manifestations have been reported in immunocompromised patients, but brain abscesses are rare. [ABSTRACT FROM AUTHOR]