학술논문
Fulminant Late-Onset Sepsis in a Neonatal Intensive Care Unit, 1988-1997, and the Impact of Avoiding Empiric Vanocomycin Therapy.
Document Type
Article
Source
Subject
*SEPTICEMIA in children
*VANCOMYCIN
*NEONATAL diseases
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Language
ISSN
0031-4005
Abstract
Conclusions. These data suggest that empiric antibiotics selected for treatment of suspected sepsis in infants >3 days old need to effectively treat Gram-negative pathogens, particularly Pseudomonas sp., because these organisms, although less frequent, are strongly associated with fulminant late-onset sepsis in the NICU. Avoiding empiric vancomycin therapy seemed to be a reasonable approach to late-onset sepsis, because of the very low frequency of fulminant sepsis caused by coagulase-negative staphylococci. Pediatrics 2000;106:1387-1390; sepsis, neonate, Pseudomonas aeruginosa, coagulase-negative staphylococcus. [ABSTRACT FROM AUTHOR]