학술논문

Metabotropic glutamate receptors on peripheral sensory neuron terminals as targets for the development of novel analgesics.
Document Type
Article
Source
Molecular Psychiatry. 2001, Vol. 6 Issue 6, p615. 3p.
Subject
*SENSORY neurons
*NOCICEPTORS
*TISSUES
Language
ISSN
1359-4184
Abstract
Studies the importance of metabotropic glutamate receptors (mGluRs) on peripheral sensory neurons in the modulation of nociceptive transmission. Indication of the rise of glutamate levels in peripheral tissues in response to inflammation; Role for mGluR subtypes 1 and 5 in models of chronic pain state; Expression of mGluR5 in sensory neurons.