학술논문
SYNTHESIS OF SOME 2-[(BENZAZOLE-2-YL)THIO]-DIPHENYLMETHYLACETAMIDE DERIVATIVES AND THEIR ANTIMICROBIAL ACTIVITY.
Document Type
Article
Source
Subject
*ORGANIC synthesis
*ISOINDOLE
*ANTI-infective agents
*BENZIMIDAZOLES
*THIAZOLES
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Language
ISSN
1042-6507
Abstract
Some 2-[(benzazole-2-yl)thio]diphenylmethylacetamide[3pc] derivatives were synthesized by reacting 2-chloroacethylaminodiphenylmethane with benzazole-2-thions. The structure elucidation of the compounds was performed by IR,1H NMR, and MS-FAB spectral data.Antimicrobial activity of the compounds was examined. Some of the compounds have shown similar antifungal activities against C. albicans when compared with ketoconazole. It was also observed that some of these compounds have moderate antimicrobial activity when compared with chloramphenicole. [ABSTRACT FROM AUTHOR]