학술논문
Clonal cooperation through soluble metabolite exchange facilitates metastatic outgrowth by modulating Allee effect.
Document Type
Article
Author
Hershey, Benjamin J.; Barozzi, Sara; Orsenigo, Fabrizio; Pompei, Simone; Iannelli, Fabio; Kamrad, Stephan; Matafora, Vittoria; Pisati, Federica; Calabrese, Ludovico; Fragale, Giuseppe; Salvadori, Giulia; Martini, Emanuele; Totaro, Maria Grazia; Magni, Serena; Rui Guan; Parazzoli, Dario; Maiuri, Paolo; Bachi, Angela; Patil, Kiran R.; Lagomarsino, Marco Cosentino
Source
Subject
Language
ISSN
2375-2548
Abstract
The article provides insights into the genetic and phenotypic heterogeneity within cancer cell populations and its role in tumor establishment and progression. It discusses how ecological interactions among distinct clonal populations within tumors contribute to their overall fitness, challenging traditional models of tumor growth.