부산대학교 도서관

Background and Aim Endoscopic retrograde cholangiopancreatography ( ERCP) in patients with roux-en-Y anastomosis ( REYA) is challenging. Use of double balloon enteroscope-assisted ERCP ( DBE- ERCP) has been successful. We aim to determine predictors of successful biliary cannulation with DBE- ERCP in patients with REYA. Methods We retrospectively studied patients with REYA who had DBE- ERCP between 2009 and 2015. Results 86 DBE- ERCP were done on 52 patients. Patients had REYA for liver transplant ( n = 26), gastrojejunostomy ( n = 9), previous bile duct injury ( n = 9), biliary atresia ( n = 2) and other ( n = 6). The biliary-enteric anastomosis was reached in 76% and cholangiogram was successful in 70%. Highest success rates were in patients with previous bile duct injury (94%) or gastrojejunostomy (89%). Post-transplant patients had intermediate success (64%). Patients with redo surgery (46%) and childhood surgery (38%), especially Kasai procedure (20%), had low success. Patients with previous bile duct injury were more likely to succeed (94% vs 63%, P = 0.010). Those more likely to fail were patients with childhood surgery (38% vs 73%, P = 0.037), biliary atresia (20% vs 73%, P = 0.013) and second operation post-transplant (25% vs 70%, P = 0.046). Conclusion Indication for REYA impacts on successful biliary cannulation in patients undergoing DBE- ERCP. The procedure is most successful in non-liver transplant adult surgery and post-transplant patients without a second operation. It is least successful in patients with surgically corrected biliary atresia and post-transplant patients with second operation. Alternative methods of biliary access should be considered in these patients. [ABSTRACT FROM AUTHOR]