학술논문
Determination of independent predictive factors for anastomotic leak: analysis of 682 intestinal anastomoses.
Document Type
Article
Author
Source
Subject
*INTESTINAL abnormalities
*SURGICAL indications
*ARTERIOVENOUS anastomosis
*BLOOD transfusion
*MEDICAL care
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Language
ISSN
0002-9610
Abstract
BACKGROUND: The objective of this study was to identify risk factors associated with intestinal anastomotic leakage in order to practically assist in surgical decision making. METHODS: A retrospective review of an academic surgery database was performed over 5 years to identify patients who had intestinal (small bowel and colon) anastomoses to determine independent pre-dictors of anastomotic leakage. RESULTS: Over the study period, 682 patients were identified with intestinal anastomoses; the over-all leak rate was 5.6% (38/682). In bivariate analysis, 9 factors were associated with anastomotic leaks. Of these, 3 were found to be independent predictors of anastomotic leakage using a logistic regression model: anastomotic tension (odds ratio [OR] = 10.1, 95% Confidence Interval [CI] 1.3 to 76.9), use of drains (OR = 8.9, 95% CI 4.3 to 18.4), and perioperative blood transfusion (OR = 4.2, 95% CI 1.4 to 12.3). CONCLUSIONS: The recognition of factors associated with anastomotic leakage after intestinal op-erations can assist surgeons in mitigating these risks in the perioperative period and guide intraoperative decisions. [ABSTRACT FROM AUTHOR]