학술논문

Treatment dropout after pregnancy: a study of women living with HIV in Rio de Janeiro.
Document Type
Article
Source
AIDS Care. Oct2020, Vol. 32 Issue 10, p1283-1289. 7p. 1 Diagram, 2 Charts.
Subject
*CLINICAL drug trials
*HIV prevention
*AGE distribution
*CHI-squared test
*CONFIDENCE intervals
*STATISTICAL correlation
*DRUGS of abuse
*FISHER exact test
*HIV infections
*HIV-positive persons
*LONGITUDINAL method
*MEDICAL records
*MOTHERS
*PATIENT compliance
*POSTNATAL care
*STATISTICS
*SUBSTANCE abuse
*LOGISTIC regression analysis
*CROSS-sectional method
*RETROSPECTIVE studies
*VERTICAL transmission (Communicable diseases)
*DATA analysis software
*ANTI-HIV agents
*DESCRIPTIVE statistics
*ACQUISITION of data methodology
*ODDS ratio
Language
ISSN
0954-0121
Abstract
Despite the investment in prevention of mother-to-child transmission of HIV, there is still little data about the proportion of women that are retained in treatment after pregnancy in Brazil. Research worldwide shows that a significant proportion of women drop out of treatment after pregnancy. The aim of this study was to identify factors associated with treatment dropout of women that received prenatal care at a federal hospital in Rio de Janeiro between 2016 and 2017 and abandoned treatment after pregnancy. This was a retrospective cohort study using data on prescription refills and hospital medical records. Cross-sectional analysis of data from 454 women showed that 18% were not on cART after pregnancy. Illicit drug use during pregnancy, being less than 35 years old, and being aware of HIV diagnosis before conceiving but not taking cART were factors associated with treatment interruption postpartum. The high prevalence of interruption of HIV treatment after pregnancy suggests that there is a need for better post-natal care to increase adherence in this population. [ABSTRACT FROM AUTHOR]