학술논문

5-oxoprolinuria (Pyroglutamic Aciduria) and Metabolic Acidosis: Unraveling the Mystery.
Document Type
Article
Source
Indian Journal of Critical Care Medicine. Jul2019, Vol. 23 Issue 7, p342-343. 2p.
Subject
*ACETAMINOPHEN
*ACIDOSIS
*CONVALESCENCE
*CRITICAL care medicine
*HOSPITAL emergency services
*MEDICAL students
*PHYSICIANS
*RISK assessment
*ACYCLIC acids
*ACETYLCYSTEINE
*DISEASE risk factors
*OLD age
Language
ISSN
0972-5229
Abstract
A case of high anion gap metabolic acidosis (HAGMA) and high level of 5-oxoprolinuria were noticed in an elderly female of 66 years who had multiple risk/precipitating factors and recovered well with N-acetyl cysteine infusion. This is reported in view of its rarity and to create awareness of this entity among medical students and practicing physicians who handles such cases in emergency room or critical care unit. Moreover they have to remember and investigate the cases of metabolic acidosis for 5-oxoprolinuia especially in susceptible individuals who are on paracetamol with or without other precipitating factors. [ABSTRACT FROM AUTHOR]