학술논문
Palladium-Catalyzed Synthesis of Allylic Ureas via an Isocyanate Intermediate.
Document Type
Article
Author
Source
Subject
*ALLYL compound synthesis
*PALLADIUM catalysts
*UREA synthesis
*ISOCYANATES
*AMINES
*CARBONATES
*CATALYSIS research
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Language
ISSN
1434-193X
Abstract
A palladium-catalyzed coupling of allylic carbonates with trimethylsilylisocyanate to provide allylic isocyanates is reported. Amines are added in a second step to yield allylic ureas in this one-pot procedure. Use of a bidentate phosphine ligand with a large bite angle was found to be important in this transformation. The scope of allylic carbonates has been examined, as well as amines compatible with these reaction conditions. [ABSTRACT FROM AUTHOR]