학술논문
Non-Leishmania Parasite in Fatal Visceral Leishmaniasis-Like Disease, Brazil.
Document Type
Journal Article
Author
Maruyama, Sandra R.; de Santana, Alynne K. M.; Takamiya, Nayore T.; Takahashi, Talita Y.; Rogerio, Luana A.; Oliveira, Caio A. B.; Milanezi, Cristiane M.; Trombela, Viviane A.; Cruz, Angela K.; Jesus, Amélia R.; Barreto, Aline S.; da Silva, Angela M.; Almeida, Roque P.; Ribeiro, José M.; Silva, João S.
Source
Subject
*LEISHMANIA mexicana
*EMERGING infectious diseases
*PARASITES
*SEQUENCE analysis
*CLASSIFICATION of protozoa
*PROTOZOA
*RESEARCH
*LEISHMANIASIS
*DNA
*BIOLOGICAL evolution
*ANIMAL experimentation
*RESEARCH methodology
*EVALUATION research
*MEDICAL cooperation
*COMPARATIVE studies
*PROTOZOAN diseases
*GENES
*MICE
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Language
ISSN
1080-6040
Abstract
Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis-like illness in Brazil. The parasites infected mice and reproduced the patient's clinical manifestations. Molecular epidemiologic studies are needed to ascertain whether a new infectious disease is emerging that can be confused with leishmaniasis. [ABSTRACT FROM AUTHOR]