학술논문

Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs.
Document Type
Article
Source
Clinical Case Reports. Nov2019, Vol. 7 Issue 11, p2156-2164. 9p.
Subject
*CELLULAR therapy
*MICRORNA
*RECTAL cancer
*CANCER treatment
Language
ISSN
2050-0904
Abstract
A 60‐year‐old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC‐ACT) causing induction of anti‐oncogenic and anti‐PD‐L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC‐ACT, metastases have been arrested, and the patient reports good quality of life. [ABSTRACT FROM AUTHOR]