부산대학교 도서관

Background: Little is known about improving physical activity (PA) and diet during and after chemotherapy for breast cancer. This secondary analysis examines changes in PA and diet quality during a yearlong intervention for patients with breast cancer undergoing chemotherapy and evaluates factors associated with these changes. Methods: Newly diagnosed patients with breast cancer (N = 173) undergoing chemotherapy were randomized to a year‐long nutrition and exercise intervention (n = 87) or usual care (UC, n = 86). Mixed models compared 1‐year changes in PA and diet quality via the Healthy Eating Index (HEI)‐2015 by study arm. Among the intervention group, baseline factors associated with change in PA and diet were assessed with multivariable linear and logistic regression. Results: At 1 year, compared with UC, the intervention arm increased PA more (mean difference = 136.1 minutes/week; 95% CI, 90.2–182.0), participated in more strength training (56% vs. 15%; p <.001), and had suggestive improvements in HEI‐2015 (mean difference = 2.5; 95% CI, –0.3 to 5.3; p =.08). In the intervention arm, lower fatigue was associated with improved PA (p =.04) and higher education was associated with improved HEI‐2015 (p =.001) at 1 year. Higher HEI‐2015 (p =.04) and married/living with someone (p =.05) were associated with higher odds of participating in strength training at 1 year. Conclusions: This year‐long lifestyle intervention for patients with breast cancer undergoing chemotherapy resulted in increases in PA and suggestive improvements in diet quality. Behavior change was associated with baseline fatigue, diet quality, education, and married/living with someone. Addressing these factors in interventions may improve uptake of lifestyle behaviors in trials during and after chemotherapy. This secondary analysis of the Lifestyle, Exercise, and Nutrition Early After Diagnosis trial explored changes in physical activity and diet quality during a year‐long lifestyle intervention for patients with breast cancer that started at the beginning of chemotherapy and evaluated baseline factors associated with behavior change. Although women enrolled in the trial improved their physical activity and had suggestive improvements in diet quality from the start of chemotherapy through 1 year, considering sociodemographic factors including education, being married/living with someone, as well as baseline levels of fatigue may be important for future interventions seeking to achieve maximum positive behavior change during and after chemotherapy. [ABSTRACT FROM AUTHOR]