부산대학교 도서관

Although the protozoan parasite I Cryptosporidium i spp. was recognized as a human pathogen in 1976 [[1]], it was only after a major outbreak in 1993 that sickened more than 400,000 and killed 69 in Milwaukee, Wisconsin, United States of America [[2]], that its impact as a diarrheal disease-causing pathogen began to be widely appreciated. We highlight below the reasons why cryptosporidiosis strongly deserves inclusion on the FDA list of tropical diseases and how this could help stimulate development of improved therapies. This same study also revealed that, beyond the acute effects of cryptosporidiosis diarrhea that account for 4.2 million disability-adjusted life years (DALYs) in children under 5 years, cryptosporidiosis is responsible for an additional burden of malnutrition and growth stunting that causes another 7.85 million DALYs. [Extracted from the article]