학술논문

Hashimoto Encephalopathy Presenting With Stroke-Like Episodes in an Adolescent Female: A Case Report and Literature Review.
Document Type
Journal Article
Source
Pediatric Neurology. Jun2016, Vol. 59, p62-70. 9p.
Subject
*AUTOIMMUNE thyroiditis
*FEMALES
*STROKE
*COGNITIVE ability
*STATUS epilepticus
*IODIDE peroxidase
*DIAGNOSIS
*AUTOIMMUNE disease treatment
*DISEASES
Language
ISSN
0887-8994
Abstract
Background: Hashimoto encephalopathy is a rare form of encephalopathy thought to be of autoimmune etiology. Cognitive changes and seizures are the most commonly reported presenting manifestation. Stroke-like episodes have also been documented in these individuals. We describe a rare adolescent with Hashimoto encephalopathy who presented with stroke-like symptoms.Patient Description: A previously well 15-year-old girl experienced sudden-onset language disturbance and right hemiparesis. Her symptoms resolved, but weeks later, she began experiencing refractory seizures, episodes of status epilepticus, and cognitive decline. An extensive evaluation was unremarkable, but thyroid peroxidase antibodies were elevated, and a diagnosis of Hashimoto encephalitis was made. Steroid therapy was initiated, and her symptoms resolved with return to baseline cognitive function.Conclusion: Hashimoto encephalopathy is a highly treatable condition that may be considered in the differential diagnosis of children and adolescents presenting with stroke-like symptoms. [ABSTRACT FROM AUTHOR]