학술논문

Succimer chelation in a patient with mercury-associated parkinsonism.
Document Type
Article
Source
Clinical Toxicology (15563650). Jan2024, Vol. 62 Issue 1, p65-66. 2p.
Subject
*METHYLMERCURY
*PARKINSONIAN disorders
*SINGLE-photon emission computed tomography
*CHELATION
*MERCURY vapor
Language
ISSN
1556-3650
Abstract
This article discusses a case of a 56-year-old man who presented with symptoms of parkinsonism, including tremors, stiffness, slow movements, and depression. The patient had a history of exposure to diesel oil and consumed deep-sea fish regularly. Blood tests revealed an abnormal mercury concentration. The patient was prescribed carbidopa and levodopa for symptomatic relief, but there was minimal improvement. Succimer, a chelating agent, was then administered, leading to a significant improvement in symptoms. The article emphasizes the importance of considering mercury exposure as a potential cause of parkinsonism and suggests further research on the efficacy of succimer in treating mercury-associated parkinsonism. [Extracted from the article]