학술논문

Induced pluripotent stem cells from highly endangered species.
Document Type
Article
Source
Nature Methods. Oct2011, Vol. 8 Issue 10, p829-831. 3p. 2 Graphs.
Subject
*PLURIPOTENT stem cells
*ENDANGERED species
*WHITE rhinoceros
*FIBROBLASTS
*IMMUNOCYTOCHEMISTRY
Language
ISSN
1548-7091
Abstract
For some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent extinction. We report generation of induced pluripotent stem cells (iPSCs) from two endangered species: a primate, the drill, Mandrillus leucophaeus and the nearly extinct northern white rhinoceros, Ceratotherium simum cottoni. iPSCs may eventually facilitate reintroduction of genetic material into breeding populations. [ABSTRACT FROM AUTHOR]