학술논문

A suggested new bacteriophage genus: 'Viunalikevirus'.
Document Type
Article
Source
Archives of Virology. Oct2012, Vol. 157 Issue 10, p2035-2046. 12p. 1 Color Photograph, 1 Black and White Photograph, 4 Diagrams, 4 Charts.
Subject
*BACTERIOPHAGE genetics
*VIRAL genomes
*GENETIC regulation
*VIRAL proteins
*THYMINE
*TRANSFER RNA
*MICROORGANISMS
Language
ISSN
0304-8608
Abstract
We suggest a bacteriophage genus, 'Viunalikevirus', as a new genus within the family Myoviridae. To date, this genus includes seven sequenced members: Salmonella phages ViI, SFP10 and ΦSH19; Escherichia phages CBA120 and PhaxI; Shigella phage phiSboM-AG3; and Dickeya phage LIMEstone1. Their shared myovirus morphology, with comparable head sizes and tail dimensions, and genome organization are considered distinguishing features. They appear to have conserved regulatory sequences, a horizontally acquired tRNA set and the probable substitution of an alternate base for thymine in the DNA. A close examination of the tail spike region in the DNA revealed four distinct tail spike proteins, an arrangement which might lead to the umbrella-like structures of the tails visible on electron micrographs. These properties set the suggested genus apart from the recently ratified subfamily Tevenvirinae, although a significant evolutionary relationship can be observed. [ABSTRACT FROM AUTHOR]