학술논문
Cure of Limb-Threatening XDR Pseudomonas aeruginosa Infection: Combining Genome Sequencing, Therapeutic Drug Level Monitoring, and Surgical Debridement.
Document Type
Article
Author
Source
Subject
*DRUG monitoring
*PSEUDOMONAS aeruginosa infections
*NUCLEOTIDE sequencing
*DRUG utilization
*PSEUDOMONAS aeruginosa
*DEBRIDEMENT
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Language
ISSN
2328-8957
Abstract
We describe a case of limb-threatening osteomyelitis and metalware infection with carbapenemase-producing extensively drug-resistant Pseudomonas aeruginosa successfully cured with aggressive surgical debridement and combined intravenous fosfomycin and colistin. Real-time therapeutic drug monitoring was used to maximize probability of efficacy and minimize potential for toxicity. [ABSTRACT FROM AUTHOR]