학술논문
Distinguishing Zika and Dengue Viruses through Simple Clinical Assessment, Singapore.
Document Type
Journal Article
Author
Yan, Gabriel; Siew Seen Ho; Oon, Jolene; Smitasin, Nares; Long Pang; Cook, Alex R.; Tambyah, Paul A.; Fisher, Dale; Bagdasarian, Natasha; Chai, Louis Yi Ann; Mar Soe Win; Ho, Hanley J.; Wong, Joshua G. X.; Lye, David C.; Yee Sin Leo; Chow, Angela; Ai Leng Khoo; Chun Kiat Lee; Yan, Benedict; Jureen, Roland
Source
Subject
*DENGUE viruses
*ZIKA virus
*CONJUNCTIVITIS
*LOGISTIC regression analysis
*DIAGNOSIS of fever
*ANIMAL experimentation
*COMPARATIVE studies
*DENGUE
*DIFFERENTIAL diagnosis
*FEVER
*FLAVIVIRUSES
*LONGITUDINAL method
*RESEARCH methodology
*MEDICAL cooperation
*MOSQUITOES
*MYALGIA
*RESEARCH
*EVALUATION research
*CASE-control method
*RECEIVER operating characteristic curves
*LEUKOCYTE count
*PLATELET count
*VIRAL conjunctivitis
*INFECTIOUS disease transmission
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Language
ISSN
1080-6040
Abstract
Dengue virus and Zika virus coexist in tropical regions in Asia where healthcare resources are limited; differentiating the 2 viruses is challenging. We showed in a case-control discovery cohort, and replicated in a validation cohort, that the diagnostic indices of conjunctivitis, platelet count, and monocyte count reliably distinguished between these viruses. [ABSTRACT FROM AUTHOR]