학술논문

SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity.
Document Type
Article
Source
Science Advances. 6/9/2023, Vol. 9 Issue 23, p1-14. 14p.
Subject
*SARS-CoV-2
*VIRUS diseases
Language
ISSN
2375-2548
Abstract
The article discusses effect of structural and computational design severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral fusogens on neuronal activity. It mentions that SARS-CoV-2 infection induces fusion between neurons and glia in mouse and human brain organoids, where it mentions that neuronal fusion is a progressive and can lead to the formation of multicellular syncytia which further compromises neuronal activity.