부산대학교 도서관

ACTH and alpha-subunit are co-expressed in rare human pituitary corticotroph cell adenomas proposed to originate from ACTH-committed early pituitary progenitor cells. Keywords: adrenocortical cells; choristoma; corticotroph tumour EN adrenocortical cells choristoma corticotroph tumour 1 6 6 02/03/22 20220215 NES 220215 We describe a rare TPIT-positive corticotroph PitNET that is admixed with SF1-positive adrenocortical cells. Only one mitotic figure in a small tumour cell was found across four haematoxylin and eosin (H&E) slides; the Ki-67 labelling index was low at 1.6% and predominantly immunostained the nuclei of small tumour cells. The smaller cells were sometimes arranged at the periphery of the cytoplasm of the larger cells, as though they might be within the larger cells (Figure 1C). [Extracted from the article]