부산대학교 도서관

Purpose: High density materials that are used in stabilization hardware potentially pose an issue regarding postoperative radiation therapy. This work investigates radiation therapy workflow steps in situations where hybrid implants consisting of titanium and carbon-fiber-composites (CFP-T) were used for stabilization and the radiation therapy is delivered using a robotic device. Methods: To investigate the quality of the image registration and delineation, these tasks were carried out using CT images from two patients with CFP-T implants in place. Treatment plans were created on an anthropomorphic phantom equipped with CFP-T spine stabilization to assess the accuracy of the calculated dose distributions. The phantom allows to measure the dose distribution near to the high density material using radiochromic film. Furthermore, a regular machine QA end-to-end (E2E) test was modified to test the image guidance procedure for the anthropomorphic phantom. Results: It was possible to delineate the patient cases with the CFP-T implants according to international consensus. The gamma passing rates of the comparison between the calculated and measured dose distributions were above 97% using the following criteria: 5% (of the maximal dose), 1 mm with 20% dose threshold. The modified E2E test was as accurate as the unmodified standard tests (targeting accuracy < 0.95 mm). Conclusion: No critical impediments regarding postoperative spine irradiations in presence of CFP-T implants were identified in this work. [ABSTRACT FROM AUTHOR]