부산대학교 도서관

Both Fourier Transform Infrared (FTIR) and Raman spectroscopy have been applied to the in vitro characterisation of biomaterials, mainly surface reactions leading to the formation of a biologically active hydroxycarbonate apatite (HCA) layer on the sample surface when immersed in simulated body fluids (SBF). The HCA layer indicates the degree of bioactivity of the sample, because it leads to a strong bond between the biomaterial and living tissue. Reflection measurements using FTIR allow quick, non-destructive detection of the HCA layer for solid and powder samples. Due to the low Raman scattering efficiency and low absorption of water in the visible-near infrared region, Raman micro-spectroscopy was successfully used for the in situ characterisation of 20 and 40 μm diameter 45S5 Bioglass [ABSTRACT FROM AUTHOR]