학술논문

IL‐4 and IL‐13 both contribute to the homeostasis of human conjunctival goblet cells in vitro.
Document Type
Article
Source
Allergy. Aug2022, Vol. 77 Issue 8, p2555-2558. 4p.
Subject
*HOMEOSTASIS
*UNFOLDED protein response
*ALLERGIC conjunctivitis
Language
ISSN
0105-4538
Abstract
IL-4 and IL-13 both contribute to the homeostasis of human conjunctival goblet cells in vitro (C) Functional redundant effects of IL-13 and IL-4 on primary human CGC proliferation and mucin mRNA expression. IL-13 and IL-4 promoted CGC cell proliferation comparably, whereas IFN- had a strong negative impact on cell proliferation and viability (Figure 1C and Figure S1A). [Extracted from the article]