학술논문

Adult neural stem cells have latent inflammatory potential that is kept suppressed by Tcf4 to facilitate adult neurogenesis.
Document Type
Article
Source
Science Advances. 5/19/2021, Vol. 7 Issue 21, p1-11. 11p.
Subject
*DEVELOPMENTAL neurobiology
*NEURAL stem cells
*ADULTS
*MONONUCLEAR leukocytes
*GLIAL fibrillary acidic protein
Language
ISSN
2375-2548
Abstract
The article presents a study examining how adult neural stem cells have latent inflammatory potential that is kept suppressed by Tcf4 to facilitate adult neurogenesis. It demonstrate that the adult hippocampal neural progenitors harbor an inflammatory potential that is proactively suppressed by transcription factor 4 (Tcf4).