학술논문
Effective synthesis of symmetrical oxygen- and nitrogen-heterocycles from electron-deficient alkynes via the catalysis of electrogenerated base and Fe3+ ions
Document Type
Article
Source
Subject
*ORGANIC synthesis
*OXYGEN
*NITROGEN
*HETEROCYCLIC compounds
*ALKYNES
*CATALYSIS
*ELECTROCHEMISTRY
*IRON ions
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Language
ISSN
0040-4020
Abstract
Abstract: An efficient method has been developed for the synthesis of oxygen- and nitrogen-heterocycles from electron-deficient alkynes and alcohol or amines via electrochemically induced two-step process. The first step involves that the electrogenerated base (EGB) catalyzes hydroalcoholization or hydroamination process. In the second step, Fe3+ ions and strong bases electrogenerated can synergically catalyze the cyclization process to give symmetrical heterocycles. Some key factors were investigated and the reaction mechanism was discussed. [Copyright &y& Elsevier]