학술논문

The current state of molecular profiling in gastrointestinal malignancies.
Document Type
Article
Source
Biology Direct. 6/7/2022, Vol. 17 Issue 1, p1-22. 22p.
Subject
*GASTROINTESTINAL cancer
*INDIVIDUALIZED medicine
*MOBILE geographic information systems
*CANCER prognosis
*PANCREATIC cancer
*NUCLEOTIDE sequencing
Language
ISSN
1745-6150
Abstract
This is a review of the current state of molecular profiling in gastrointestinal (GI) cancers and what to expect from this evolving field in the future. Individualized medicine is moving from broad panel testing of numerous genes or gene products in tumor biopsy samples, identifying biomarkers of prognosis and treatment response, to relatively noninvasive liquid biopsy assays, building on what we have learned in our tumor analysis and growing into its own evolving predictive and prognostic subspecialty. Hence, the field of GI precision oncology is exploding, and this review endeavors to summarize where we are now in preparation for the journey ahead. [ABSTRACT FROM AUTHOR]