부산대학교 도서관

Objectives: Dental caries is the most common chronic disease worldwide and different forms of fluoride are considered to be a helpful preventive tool. Producing substances in nanoscale can significantly improve their mechanical and chemical properties. Therefore, the aim of the present study was to assess nano NaF gel regarding fluoride uptake when applied on enamel of deciduous teeth. Method: A total number of 40 enamel samples were obtained from caries-free primary canines. Samples were randomly assigned to four groups (G1=NaF5%, G2=NanoNaF 1%, G3=Nano NaF 5%, G4= control) (10 samples in each group). Each group was divided into two subgroups named sound (S) and demineralized (D) (5 samples in each subgroup). Half of the samples in each group were demineralized then enamel samples were treated with the fluoride type specified for each group. Finally, SEM-EDX microscope was used to determine fluoride uptake. Data were analyzed using the following statistical tests; one-way Anova, Kruskal Wallis-H, Tukey post hoc test and Dunn's post hoc test. Results: Fluoride was not detected in G1 and G4 groups. However G2 and G3 groups revealed a significant increase regarding fluoride content. Fluoride content was significantly higher in samples with higher Ca/P ratio. Significance: Considering the high fluoride uptake achieved by Nano NaF, it might be possible to decrease the dose of fluoride needed at each dental appointment meanwhile gain better results regarding possible caries prevention. Also, we may be able to increase the time intervals between fluoride therapy sessions, especially important in young children lacking enough cooperation. [ABSTRACT FROM AUTHOR]