학술논문
Correction to: The current standing of autologous haematopoietic stem cell transplantation for the treatment of multiple sclerosis.
Document Type
Correction Notice
Author
Source
Subject
*HEMATOPOIETIC stem cell transplantation
*STEM cell treatment
*MULTIPLE sclerosis
*REGULATORY T cells
*KILLER cells
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*
*
*
Language
ISSN
0340-5354
Abstract
In patients with MS, autoreactive T cell clones that have escaped immune tolerance mechanisms contribute to pathogenesis by effecting neuroinflammation, along with B cells and natural killer (NK) cells. Following the other regimens, engrafted cells are thought to compete with the remaining immune cells and then out-compete and predominate the old T cell clones. T cell maturation occurs within the thymus, with the bone marrow producing thymocytes that then undergo a complex maturation process within the thymus, producing regulatory T cells (Treg), CD4+ T cells and CD8+ T cells. [Extracted from the article]